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Devil's Claw (Harpagophytum procumbens) plant
Skeletal

Devil's Claw (Harpagophytum procumbens)

Photo: Roger Culos · CC BY-SA 3.0

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  • 3 conditions
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Overview

Devil’s claw (Harpagophytum procumbens) is a trailing perennial native to southern Africa, named for its hooked, woody fruits. For millennia, indigenous peoples have relied on its tuber to treat pain, fever, and digestive ailments. In modern herbalism, devil’s claw is best known for its anti-inflammatory and analgesic properties, frequently employed to support joint health and reduce arthritic or lower back pain. It also acts as a bitter tonic to stimulate digestion.

Traditional uses & properties

Analgesic & Anti-inflammatory: Alleviates pain and stiffness in arthritis, gout, and muscle aches. Bitter Digestive Stimulant: Encourages gastric secretions, potentially aiding poor digestion but best avoided if ulcers are present. Cooling & Drying: Reduces heat, swelling, and dampness (in the sense of traditional energetics).

Traditional preparations

Traditional texts describe the preparations below, and where those texts give specific amounts, the amounts are quoted here as part of that record. This is a record of historical practice, not a dosage recommendation - the figures are what the sources say, not what HerbMate tells you to take. Amounts, potency, and safe use vary enormously by preparation, plant part, and person.

CAPSULE OR POWDER

500-1,000 mg, 2-3 times daily

TINCTURE

Dried root (1:5, 25% alcohol); 1-2 ml (0.2-0.4 tsp.) 3 times daily

How these are made

Safety & precautions

Gastric/Duodenal Ulcers: Not advised if you have active peptic ulcers. Gallstones or Pregnancy: Use cautiously under professional guidance; devil’s claw may stimulate digestive secretions and uterine activity.

Drug & food interactions

Limited evidence is available. Devil’s claw does not appear to affect blood pressure, and its theoretical interaction with drugs with antiplatelet effects seems unlikely to be of practical relevance; however, it may increase the anticoagulant effects of drugs such as warfarin.

Food
No interactions found.
Antihypertensives
Devil’s claw does not appear to affect blood pressure and is therefore unlikely to interact with antihypertensives to a clinically relevant extent, although further study is needed to confirm this. In a randomised, placebo-controlled, 4-week study, a Devil’s claw extract was studied for the possible treatment of low back pain in 109 patients. One patient had an episode of tachycardia while on holiday, and stopped taking the herbal medicine. When he returned from holiday, Devil’s claw was restarted and was well tolerated. It was suggested that this adverse event was due to the change in climate rather than the medication. Furthermore, in the study, there was no significant change in systolic and diastolic blood pressure or heart rate between the beginning and the end of the study, and between Devil’s claw and placebo recipients. The Devil’s claw extract used in this study was given at a dose of 800 mg three times daily, equivalent to a daily dose of 50 mg of harpagoside.
Antiplatelet drugs and NSAIDs
The interaction between Devil’s claw and antiplatelet drugs and NSAIDs is based on a prediction only.
Warfarin and related drugs
Devil’s claw may increase the effects of warfarin, and possibly other coumarins. A case report from a 5-year toxicological study describes the development of purpura in a patient following the concurrent use of Devil’s claw and warfarin.
Herbal medicines
No interactions found.

These entries keep the wording of the reference they come from, and three phrases mean three different things. "No interactions found" means the source looked for reports of that pairing and found none. "No data found" means nothing has been published either way. "Based on experimental evidence only" means the effect has been seen in a laboratory or animal study but not in people - a reason for caution, not a report of harm.

Habitat

Found mainly in Namibia, Botswana, and parts of South Africa, devil’s claw is a protected plant due to overharvesting in the wild. It prefers clay or sandy soils and disturbed areas like roadsides. It is grown from seed in spring, with young tubers harvested in autumn and carefully separated from the roots to preserve medicinal potency.

Traditionally used for

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Frequently asked questions

What is Devil's Claw (Harpagophytum procumbens) traditionally used for?

Traditional sources describe Devil's Claw (Harpagophytum procumbens) as follows: Analgesic & Anti-inflammatory: Alleviates pain and stiffness in arthritis, gout, and muscle aches. Bitter Digestive Stimulant: Encourages gastric secretions, potentially aiding poor digestion but best avoided if ulcers are present. Cooling & Drying: Reduces heat, swelling, and dampness (in the sense of traditional energetics).

How is Devil's Claw (Harpagophytum procumbens) prepared?

Traditional texts describe the preparations below, and where those texts give specific amounts, the amounts are quoted here as part of that record. This is a record of historical practice, not a dosage recommendation - the figures are what the sources say, not what HerbMate tells you to take. Amounts, potency, and safe use vary enormously by preparation, plant part, and person. CAPSULE OR POWDER: 500-1,000 mg, 2-3 times daily TINCTURE: Dried root (1:5, 25% alcohol); 1-2 ml (0.2-0.4 tsp.) 3 times daily

What safety cautions apply to Devil's Claw (Harpagophytum procumbens)?

Gastric/Duodenal Ulcers: Not advised if you have active peptic ulcers. Gallstones or Pregnancy: Use cautiously under professional guidance; devil’s claw may stimulate digestive secretions and uterine activity.