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Blue Cohosh (Caulophyllum thalictroides) plant
Female Reproductive

Blue Cohosh (Caulophyllum thalictroides)

Photo: H. Zell · CC BY-SA 3.0

  • Female Reproductive
  • 4 conditions
  • Licensed photo

Overview

Blue cohosh is an upright perennial herb reaching 3 feet in height, with large three-lobed leaves, yellow to purple flowers, and striking blue berries. It grows wild in much of eastern North America from Manitoba to Alabama, preferring woodland valleys and damp, north-facing slopes. The name 'cohosh' comes from the Algonquin language, and the plant was a popular remedy among many Native American tribes.

Traditional uses & properties

The root and rhizome contain alkaloids, steroidal saponins, and resin.

Amounts reported by sources

Preparation amounts are not shown for this herb. It is toxic, restricted, or otherwise unsafe to self-dose - the margin between a traditional dose and a harmful one is too small to publish as reference material. If you are considering it, that conversation belongs with a doctor or a qualified practitioner, not a website.

Safety & precautions

Use only under professional supervision. Do not take during pregnancy or while trying to conceive, as it stimulates uterine contractions and could induce miscarriage. Avoid during heavy menstrual bleeding. NCCIH says the use of blue cohosh to induce labor has been associated with life-threatening complications in the infant, including seizures, and that blue cohosh may cause high blood pressure, high blood sugar and chest pain. The plant can be toxic and can cause contact dermatitis. Not recommended while breastfeeding.

Educational reference only - not medical advice. Herbs can interact with medications. Consult a qualified healthcare provider before use. Full disclaimer.

Drug interactions

Interaction data is not available for this herb - talk to a pharmacist before combining it with any medication. A blank entry here means we have not documented interactions, not that none exist.

Habitat

Blue cohosh grows wild throughout much of eastern North America, from Manitoba to Alabama. It prefers woodland valleys and damp, north-facing slopes, and is mainly wild-harvested but also cultivated commercially. The root and rhizome are harvested in autumn.

Sources

The interaction notes and the statements on this page that name a source were written by HerbMate from these references, which were last checked in October 2026. They are summaries, not medical advice; ask a pharmacist about your own medicines.

  1. NCCIH (NIH): Black Cohosh (includes blue cohosh safety)

Traditionally used for

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Frequently asked questions

What is Blue Cohosh (Caulophyllum thalictroides) traditionally used for?

Traditional sources describe Blue Cohosh (Caulophyllum thalictroides) as follows: The root and rhizome contain alkaloids, steroidal saponins, and resin.

How is Blue Cohosh (Caulophyllum thalictroides) prepared?

Preparation amounts are not shown for this herb. It is toxic, restricted, or otherwise unsafe to self-dose - the margin between a traditional dose and a harmful one is too small to publish as reference material. If you are considering it, that conversation belongs with a doctor or a qualified practitioner, not a website.

What safety cautions apply to Blue Cohosh (Caulophyllum thalictroides)?

Use only under professional supervision. Do not take during pregnancy or while trying to conceive, as it stimulates uterine contractions and could induce miscarriage. Avoid during heavy menstrual bleeding. NCCIH says the use of blue cohosh to induce labor has been associated with life-threatening complications in the infant, including seizures, and that blue cohosh may cause high blood pressure, high blood sugar and chest pain. The plant can be toxic and can cause contact dermatitis. Not recommended while breastfeeding.