HerbMate
Saw Palmetto (Serenoa repens) plant
Male Reproductive

Saw Palmetto (Serenoa repens)

Photo: Ted Bodner, Southern Weed Science Society, United States · CC BY 3.0 us

  • Male Reproductive
  • 2 conditions
  • Licensed photo

Overview

Saw palmetto (Serenoa repens), also known as Sabal serrulata, is a small, slow-growing palm (to about 20 ft / 6 m) bearing fan-like fronds and white flowers that develop into dark purple to black berries. It is promoted as a dietary supplement for urinary symptoms of an enlarged prostate (BPH). NCCIH says saw palmetto is probably not helpful for urinary symptoms of an enlarged prostate.

Traditional uses & properties

Prostate Tonic: The berries are promoted for urinary symptoms of benign prostatic hyperplasia (BPH), although NCCIH says a 2023 review found saw palmetto alone provides little or no benefit.

Safety & precautions

Pregnancy, Nursing, Hormone-Sensitive Cancers: Avoid due to hormonal effects. Medication Interactions: Consult a health provider if using other drugs for hormonal balance, bleeding disorders, or blood pressure issues.

Educational reference only - not medical advice. Herbs can interact with medications. Consult a qualified healthcare provider before use. Full disclaimer.

Drug interactions

LiverTox describes few herb-drug interactions for saw palmetto, while MSK lists case reports involving bleeding. [1, 2]

Blood thinners and antiplatelet drugs
MSK cites case reports suggesting additive anticoagulant effects, and a 2014 review of warfarin case reports includes Serenoa repens (saw palmetto). [2, 3]
NSAIDs
One case report cited by MSK suggests more side effects with these drugs. [2]
Medicines broken down by liver enzymes
MSK reports laboratory inhibition of several CYP and UGT enzymes. Relevance is unknown. [2]

How to read this section: each entry is HerbMate's summary of what the cited sources report. Words such as "may", "theoretical" or "in laboratory or animal studies" mean the effect has not been confirmed in people, and "case report" means it was seen in one or a few patients. A medicine that is not listed here has not been shown to be safe with this herb. The numbers in brackets link to the sources at the foot of the page.

Habitat

Native to the southeastern U.S., typically along Atlantic and Gulf coastal plains, saw palmetto thrives in sandy, well-drained areas. The ripe berries are collected in autumn.

Sources

The interaction notes and the statements on this page that name a source were written by HerbMate from these references, which were last checked in October 2026. They are summaries, not medical advice; ask a pharmacist about your own medicines.

  1. LiverTox (NIDDK, NIH): Saw Palmetto
  2. Memorial Sloan Kettering, About Herbs: Saw Palmetto
  3. Milic N, et al. Warfarin interactions with medicinal herbs. Nat Prod Commun, 2014 (PubMed 25233607)
  4. NCCIH (NIH): Saw Palmetto

Traditionally used for

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Frequently asked questions

What is Saw Palmetto (Serenoa repens) traditionally used for?

Traditional sources describe Saw Palmetto (Serenoa repens) as follows: Prostate Tonic: The berries are promoted for urinary symptoms of benign prostatic hyperplasia (BPH), although NCCIH says a 2023 review found saw palmetto alone provides little or no benefit.

What safety cautions apply to Saw Palmetto (Serenoa repens)?

Pregnancy, Nursing, Hormone-Sensitive Cancers: Avoid due to hormonal effects. Medication Interactions: Consult a health provider if using other drugs for hormonal balance, bleeding disorders, or blood pressure issues.