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Alfalfa (Medicago sativa) plant
Head and Neck

Alfalfa (Medicago sativa)

Photo: Sten Porse · CC BY-SA 3.0

  • Head and Neck
  • 1 condition
  • Licensed photo

Overview

Alfalfa is a perennial herb that can grow to about 32 in (80 cm). It produces trifoliate leaves, flowers ranging from yellow to violet-blue, and spiraling seed pods. It has been called the “king of herbs,” with roots that can extend many feet into the ground to draw up minerals.

Traditional uses & properties

It is mineral-rich. It is traditionally taken to lower cholesterol; MSK says two small trials found that alfalfa supplements lowered cholesterol in people with high cholesterol, but larger controlled trials are needed to confirm this. Alfalfa contains phytoestrogens, which MSK says act like some human hormones; it has been used to promote menstruation, but MSK says there are no studies to support this.

Safety & precautions

Alfalfa contains canavanine, which can induce lupus-like symptoms in susceptible individuals or worsen existing autoimmune conditions. Not recommended alongside anticoagulant medications (such as warfarin) because it can interfere with blood-thinning effects. The sprouted seeds should be avoided in immunocompromised states or during pregnancy. Excessive daily consumption of seeds may lead to blood clotting problems.

Educational reference only - not medical advice. Herbs can interact with medications. Consult a qualified healthcare provider before use. Full disclaimer.

Drug interactions

Interaction data is not available for this herb - talk to a pharmacist before combining it with any medication. A blank entry here means we have not documented interactions, not that none exist.

Habitat

Originally found in Europe, Asia, and North Africa, it now grows worldwide, especially in temperate zones, often as a fodder crop. It thrives in meadows and open cultivated areas, usually harvested in the summer.

Sources

The interaction notes and the statements on this page that name a source were written by HerbMate from these references, which were last checked in October 2026. They are summaries, not medical advice; ask a pharmacist about your own medicines.

  1. Memorial Sloan Kettering, About Herbs: Alfalfa

Traditionally used for

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Frequently asked questions

What is Alfalfa (Medicago sativa) traditionally used for?

Traditional sources describe Alfalfa (Medicago sativa) as follows: It is mineral-rich. It is traditionally taken to lower cholesterol; MSK says two small trials found that alfalfa supplements lowered cholesterol in people with high cholesterol, but larger controlled trials are needed to confirm this. Alfalfa contains phytoestrogens, which MSK says act like some human hormones; it has been used to promote menstruation, but MSK says there are no studies to support this.

What safety cautions apply to Alfalfa (Medicago sativa)?

Alfalfa contains canavanine, which can induce lupus-like symptoms in susceptible individuals or worsen existing autoimmune conditions. Not recommended alongside anticoagulant medications (such as warfarin) because it can interfere with blood-thinning effects. The sprouted seeds should be avoided in immunocompromised states or during pregnancy. Excessive daily consumption of seeds may lead to blood clotting problems.