Devil's Claw (Harpagophytum procumbens) vs Gravel Root (Eupatorium purpureum)

Devil's Claw (Harpagophytum procumbens)

Gravel Root (Eupatorium purpureum)

About

Devil’s claw (Harpagophytum procumbens) is a trailing perennial native to southern Africa, named for its hooked, woody fruits. Its tuber has long been used in traditional medicine for pain, fever, and stomach complaints; MSK says no scientific evidence supports its use for digestive disorders. Today it is mostly taken for joint and back pain; MSK says small studies suggest it may help osteoarthritis of the hip or knee and back pain, but larger studies are needed.

Gravel root is an erect perennial growing to 5 feet with whorls of pointed oblong leaves and clusters of purple-pink florets. Native to eastern North America, the root is unearthed in autumn. The plant's alternative name, Joe Pye weed, honors a Native American named Joe Pye. The root was listed in the Pharmacopoeia of the United States from 1820 to 1842.

Safety & precautions

Gastric/Duodenal Ulcers: Not advised if you have active peptic ulcers. Gallstones or Pregnancy: Use cautiously under professional guidance; devil’s claw may stimulate digestive secretions and uterine activity.

Contains pyrrolizidine alkaloids. Not recommended for long-term use or for pregnant or nursing women due to potential liver toxicity from pyrrolizidine alkaloids. Use only for short-term treatment under professional guidance.

Safety text above is printed in full and is never abbreviated. For each plant’s complete precautions, drug and food interactions and preparation notes, open its own page - both are free.