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Herb comparison

Devil's Claw (Harpagophytum procumbens) vs Gravel Root (Eupatorium purpureum)

Both plants are listed as traditional remedies for 2 of the same conditions, which is why they are easy to confuse. Their descriptions and full safety notes are below, free.

Devil's Claw (Harpagophytum procumbens) plant

Devil's Claw (Harpagophytum procumbens)

Gravel Root (Eupatorium purpureum) plant

Gravel Root (Eupatorium purpureum)

About
Devil’s claw (Harpagophytum procumbens) is a trailing perennial native to southern Africa, named for its hooked, woody fruits. For millennia, indigenous peoples have relied on its tuber to treat pain, fever, and digestive ailments. In modern herbalism, devil’s claw is best known for its anti-inflammatory and analgesic properties, frequently employed to support joint health and reduce arthritic or lower back pain. It also acts as a bitter tonic to stimulate digestion.
Gravel root is an erect perennial growing to 5 feet with whorls of pointed oblong leaves and clusters of purple-pink florets. Native to eastern North America, the root is unearthed in autumn. The plant's alternative name, Joe Pye weed, honors the Native American said to have used it to cure New Englanders of typhus. Native Americans valued the herb as a diuretic and remedy for genitourinary conditions, and the root was listed in the Pharmacopoeia of the United States from 1820 to 1842, attesting to its recognized medicinal importance.
Safety & precautions
Gastric/Duodenal Ulcers: Not advised if you have active peptic ulcers. Gallstones or Pregnancy: Use cautiously under professional guidance; devil’s claw may stimulate digestive secretions and uterine activity.
Contains pyrrolizidine alkaloids. Not recommended for long-term use or for pregnant or nursing women due to potential liver toxicity from pyrrolizidine alkaloids. Use only for short-term treatment under professional guidance.

Safety text above is printed in full and is never abbreviated. For each plant’s complete precautions, drug and food interactions and preparation notes, open its own page - both are free.

Conditions that list both