Andrographis (Andrographis paniculata) vs Pau d'Arco (Tabebuia impetiginosa)

Andrographis (Andrographis paniculata)

Pau d'Arco (Tabebuia impetiginosa)

About

Andrographis, commonly known as Green Chiretta or King of Bitters, is an upright annual herb reaching approximately 3 feet in height. Native to India and cultivated throughout northern regions of India and China, this bitter medicinal plant has been valued in Ayurvedic and traditional Chinese medicine for centuries. Historically used primarily for liver support and treating infections - especially malaria - it has earned recognition for its powerful immune-boosting and protective properties. The plant thrives on plains and in forest undergrowth, where its spotted pale brown or purple flowers and long seed capsules distinguish it from other medicinal herbs.

Pau d'arco is an evergreen tree that can reach 100 feet in height, producing pink flowers. The bark of this South American tree has been treasured for centuries in traditional medicine for its extensive health benefits. Indigenous peoples including the Incas and the Callawaya valued it as a cure-all. The tree grows in both mountainous terrains high in the Andes and in low-lying areas of Paraguay and Brazil. The prized inner bark is collected from wild-growing trees throughout the year.

Safety & precautions

Do not use during pregnancy or while breastfeeding, as andrographis may have effects on fertility and uterine contractions. High doses can cause nausea, vomiting, and gastrointestinal upset. Use caution if taking antiplatelet drugs or anticoagulants like warfarin, as andrographis may have additive antiplatelet effects and could modestly increase warfarin exposure, potentially raising bleeding risk. Monitor blood glucose closely if taking antidiabetic medications, since andrographis may lower blood sugar levels. Similarly, those on antihypertensive drugs should be aware of possible additive blood pressure-lowering effects. Evidence suggests andrographis might induce certain cytochrome P450 enzymes and moderately inhibit P-glycoprotein, though clinical significance remains unclear. Extremely large doses are discouraged and professional supervision is recommended for long-term use.

If taking anticoagulant medication, use only under professional supervision. Do not take during pregnancy. Avoid if trying to conceive. High doses may cause nausea, vomiting, intestinal discomfort, and anticoagulant effects. Blood clotting disorders are a contraindication.

Safety text above is printed in full and is never abbreviated. For each plant’s complete precautions, drug and food interactions and preparation notes, open its own page - both are free.